3bi4: Difference between revisions

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-[[Image:3bi4.png|left|200px]]
-{{STRUCTURE_3bi4|  PDB=3bi4  |  SCENE=  }}
+==Crystal structures of fms1 in complex with its inhibitors==
+<StructureSection load='3bi4' size='340' side='right'caption='[[3bi4]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-===Crystal structures of fms1 in complex with its inhibitors===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3bi4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BI4 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=298:N-[(1E,2Z)-BUT-2-EN-1-YLIDENE]-N-[(2E)-BUT-2-EN-1-YLIDENE]BUTANE-1,4-DIAMINE'>298</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-[[3bi4]] is a 2 chain structure of [[Polyamine oxidase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BI4 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bi4 OCA], [https://pdbe.org/3bi4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bi4 RCSB], [https://www.ebi.ac.uk/pdbsum/3bi4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bi4 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FMS1_YEAST FMS1_YEAST] Involved in the production of beta-alanine, a precursor of pantothenic acid. Multicopy suppressor of fenpropimorph resistance.<ref>PMID:12670477</ref> <ref>PMID:14617780</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/3bi4_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bi4 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Polyamine oxidase|Polyamine oxidase]]
-[[Category: Oxidoreductase]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Hao, Q.]]
+[[Category: Hao Q]]
-[[Category: Huang, Q.]]
+[[Category: Huang Q]]
-[[Category: Enzyme-inhibitor complex]]
-[[Category: Oxidoreductase]]
-[[Category: Polyamine oxidase]]