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[[Image:1ufv.jpg|left|200px]]


{{Structure
==Crystal Structure Of Pantothenate Synthetase From Thermus Thermophilus HB8==
|PDB= 1ufv |SIZE=350|CAPTION= <scene name='initialview01'>1ufv</scene>, resolution 2.05&Aring;
<StructureSection load='1ufv' size='340' side='right'caption='[[1ufv]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[1ufv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UFV FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
|GENE= PanC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ufv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufv OCA], [https://pdbe.org/1ufv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ufv RCSB], [https://www.ebi.ac.uk/pdbsum/1ufv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ufv ProSAT], [https://www.topsan.org/Proteins/RSGI/1ufv TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PANC_THET8 PANC_THET8] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).[HAMAP-Rule:MF_00158]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ufv ConSurf].
<div style="clear:both"></div>


'''Crystal Structure Of Pantothenate Synthetase From Thermus Thermophilus HB8'''
==See Also==
 
*[[Pantothenate synthetase|Pantothenate synthetase]]
 
__TOC__
==About this Structure==
</StructureSection>
1UFV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFV OCA].
[[Category: Large Structures]]
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Single protein]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Bagautdinov, B.]]
[[Category: Bagautdinov B]]
[[Category: Kuramitsu, S.]]
[[Category: Kuramitsu S]]
[[Category: Miyano, M.]]
[[Category: Miyano M]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tahirov TH]]
[[Category: Tahirov, T H.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: CL]]
[[Category: GOL]]
[[Category: dimer]]
[[Category: domain]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rossmann fold]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:31:28 2008''

Latest revision as of 10:31, 30 October 2024

Crystal Structure Of Pantothenate Synthetase From Thermus Thermophilus HB8Crystal Structure Of Pantothenate Synthetase From Thermus Thermophilus HB8

Structural highlights

1ufv is a 2 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PANC_THET8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).[HAMAP-Rule:MF_00158]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ufv, resolution 2.05Å

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