1dqc: Difference between revisions

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-{{Seed}}
-[[Image:1dqc.png|left|200px]]
-<!--
+==SOLUTION STRUCTURE OF TACHYCITIN, AN ANTIMICROBIAL PROTEIN WITH CHITIN-BINDING FUNCTION==
-The line below this paragraph, containing "STRUCTURE_1dqc", creates the "Structure Box" on the page.
+<StructureSection load='1dqc' size='340' side='right'caption='[[1dqc]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1dqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tachypleus_tridentatus Tachypleus tridentatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DQC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 25 models</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-{{STRUCTURE_1dqc|  PDB=1dqc  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dqc OCA], [https://pdbe.org/1dqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dqc RCSB], [https://www.ebi.ac.uk/pdbsum/1dqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dqc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/P91818_TACTR P91818_TACTR]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dq/1dqc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dqc ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Tachycitin, a 73-residue polypeptide having antimicrobial activity is present in the hemocyte of horseshoe crab (Tachypleus tridentatus). The first three-dimensional structure of invertebrate chitin-binding protein was determined for tachycitin using two-dimensional nuclear magnetic resonance spectroscopy. The measurements indicate that the structure of tachycitin is largely divided into N- and C-terminal domains; the former comprises a three-stranded beta-sheet and the latter a two-stranded beta-sheet following a short helical turn. The latter structural motif shares a significant tertiary structural similarity with the chitin-binding domain of plant chitin-binding protein. This result is thought to provide faithful experimental evidence to the recent hypothesis that chitin-binding proteins of invertebrates and plants are correlated by a convergent evolution process.
-===SOLUTION STRUCTURE OF TACHYCITIN, AN ANTIMICROBIAL PROTEIN WITH CHITIN-BINDING FUNCTION===
+Chitin-binding proteins in invertebrates and plants comprise a common chitin-binding structural motif.,Suetake T, Tsuda S, Kawabata S, Miura K, Iwanaga S, Hikichi K, Nitta K, Kawano K J Biol Chem. 2000 Jun 16;275(24):17929-32. PMID:10770921<ref>PMID:10770921</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_10770921}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 1dqc" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 10770921 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_10770921}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-DQC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Tachypleus_tridentatus Tachypleus tridentatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQC OCA].
-==Reference==
-<ref group="xtra">PMID:10770921</ref><references group="xtra"/>
 [[Category: Tachypleus tridentatus]]
-[[Category: Kawabata, S.]]
+[[Category: Kawabata S]]
-[[Category: Kawano, K.]]
+[[Category: Kawano K]]
-[[Category: Miura, K.]]
+[[Category: Miura K]]
-[[Category: Suetake, T.]]
+[[Category: Suetake T]]
-[[Category: Tsuda, S.]]
+[[Category: Tsuda S]]
-[[Category: Disulfide-rich]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:55:02 2009''