1xaf: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1xaf.gif|left|200px]]


{{Structure
==Crystal Structure of Protein of Unknown Function YfiH from Shigella flexneri 2a str. 2457T==
|PDB= 1xaf |SIZE=350|CAPTION= <scene name='initialview01'>1xaf</scene>, resolution 2.01&Aring;
<StructureSection load='1xaf' size='340' side='right'caption='[[1xaf]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[1xaf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri_2a_str._2457T Shigella flexneri 2a str. 2457T]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XAF FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
|GENE= YfiH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=42897 Shigella flexneri 2a])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK10723 PRK10723]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xaf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xaf OCA], [https://pdbe.org/1xaf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xaf RCSB], [https://www.ebi.ac.uk/pdbsum/1xaf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xaf ProSAT], [https://www.topsan.org/Proteins/MCSG/1xaf TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xaf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xaf OCA], [http://www.ebi.ac.uk/pdbsum/1xaf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xaf RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/PURNU_SHIFL PURNU_SHIFL] Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has adenosine deaminase activity.[UniProtKB:P84138]
 
== Evolutionary Conservation ==
'''Crystal Structure of Protein of Unknown Function YfiH from Shigella flexneri 2a str. 2457T'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xa/1xaf_consurf.spt"</scriptWhenChecked>
1XAF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri_2a Shigella flexneri 2a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XAF OCA].
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==Reference==
  </jmolCheckbox>
Crystal structure of hypothetical protein YfiH from Shigella flexneri at 2 A resolution., Kim Y, Maltseva N, Dementieva I, Collart F, Holzle D, Joachimiak A, Proteins. 2006 Jun 1;63(4):1097-101. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16498617 16498617]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xaf ConSurf].
[[Category: Shigella flexneri 2a]]
<div style="clear:both"></div>
[[Category: Single protein]]
__TOC__
[[Category: Collart, F.]]
</StructureSection>
[[Category: Dementieva, I.]]
[[Category: Large Structures]]
[[Category: Joachimiak, A.]]
[[Category: Shigella flexneri 2a str. 2457T]]
[[Category: Kim, Y.]]
[[Category: Collart F]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Dementieva I]]
[[Category: Maltseva, N.]]
[[Category: Joachimiak A]]
[[Category: hypothetical protein]]
[[Category: Kim Y]]
[[Category: mcsg]]
[[Category: Maltseva N]]
[[Category: midwest center for structural genomic]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: shigella flexneri 2a str. 2457t]]
[[Category: structural genomic]]
[[Category: yfih]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:46:59 2008''

Latest revision as of 12:43, 25 December 2024

Crystal Structure of Protein of Unknown Function YfiH from Shigella flexneri 2a str. 2457TCrystal Structure of Protein of Unknown Function YfiH from Shigella flexneri 2a str. 2457T

Structural highlights

1xaf is a 2 chain structure with sequence from Shigella flexneri 2a str. 2457T. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.01Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PURNU_SHIFL Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has adenosine deaminase activity.[UniProtKB:P84138]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1xaf, resolution 2.01Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA