1x87: Difference between revisions

New page: left|200px<br /><applet load="1x87" size="450" color="white" frame="true" align="right" spinBox="true" caption="1x87, resolution 2.40Å" /> '''2.4A X-ray structure...
 
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[[Image:1x87.gif|left|200px]]<br /><applet load="1x87" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1x87, resolution 2.40&Aring;" />
'''2.4A X-ray structure of Urocanase protein complexed with NAD'''<br />


==About this Structure==
==2.4A X-ray structure of Urocanase protein complexed with NAD==
1X87 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] with NAD as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Urocanate_hydratase Urocanate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.49 4.2.1.49] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1X87 OCA].  
<StructureSection load='1x87' size='340' side='right'caption='[[1x87]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1x87]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X87 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x87 OCA], [https://pdbe.org/1x87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x87 RCSB], [https://www.ebi.ac.uk/pdbsum/1x87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x87 ProSAT], [https://www.topsan.org/Proteins/MCSG/1x87 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HUTU_GEOKA HUTU_GEOKA] Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.[HAMAP-Rule:MF_00577]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x8/1x87_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x87 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Urocanate hydratase]]
[[Category: Collart F]]
[[Category: Collart, F.]]
[[Category: Dementieva I]]
[[Category: Dementieva, I.]]
[[Category: Gilbreth R]]
[[Category: Gilbreth, R.]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Kossiakoff A]]
[[Category: Kossiakoff, A.]]
[[Category: Tereshko V]]
[[Category: MCSG, Midwest.Center.for.Structural.Genomics.]]
[[Category: Zaborske J]]
[[Category: Tereshko, V.]]
[[Category: Zaborske, J.]]
[[Category: NAD]]
[[Category: mcsg]]
[[Category: midwest center for structural genomics]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: putative urocanase protein]]
[[Category: structural genomics]]
 
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