1x87: Difference between revisions

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[[Image:1x87.gif|left|200px]]


{{Structure
==2.4A X-ray structure of Urocanase protein complexed with NAD==
|PDB= 1x87 |SIZE=350|CAPTION= <scene name='initialview01'>1x87</scene>, resolution 2.40&Aring;
<StructureSection load='1x87' size='340' side='right'caption='[[1x87]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
<table><tr><td colspan='2'>[[1x87]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X87 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Urocanate_hydratase Urocanate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.49 4.2.1.49] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK05414 PRK05414]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x87 OCA], [https://pdbe.org/1x87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x87 RCSB], [https://www.ebi.ac.uk/pdbsum/1x87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x87 ProSAT], [https://www.topsan.org/Proteins/MCSG/1x87 TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x87 OCA], [http://www.ebi.ac.uk/pdbsum/1x87 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1x87 RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/HUTU_GEOKA HUTU_GEOKA] Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.[HAMAP-Rule:MF_00577]
'''2.4A X-ray structure of Urocanase protein complexed with NAD'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
1X87 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X87 OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x8/1x87_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x87 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Urocanate hydratase]]
[[Category: Collart F]]
[[Category: Collart, F.]]
[[Category: Dementieva I]]
[[Category: Dementieva, I.]]
[[Category: Gilbreth R]]
[[Category: Gilbreth, R.]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Kossiakoff A]]
[[Category: Kossiakoff, A.]]
[[Category: Tereshko V]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Zaborske J]]
[[Category: Tereshko, V.]]
[[Category: Zaborske, J.]]
[[Category: mcsg]]
[[Category: midwest center for structural genomic]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: putative urocanase protein]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:10:39 2008''

Latest revision as of 03:38, 21 November 2024

2.4A X-ray structure of Urocanase protein complexed with NAD2.4A X-ray structure of Urocanase protein complexed with NAD

Structural highlights

1x87 is a 2 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

HUTU_GEOKA Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.[HAMAP-Rule:MF_00577]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1x87, resolution 2.40Å

Drag the structure with the mouse to rotate

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