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[[Image:2sgf.jpg|left|200px]]<br /><applet load="2sgf" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2sgf, resolution 1.75&Aring;" />
'''PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B'''<br />


==About this Structure==
==PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B==
2SGF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [http://en.wikipedia.org/wiki/Streptomyces_chryseus Streptomyces chryseus] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Streptogrisin_B Streptogrisin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.81 3.4.21.81] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2SGF OCA].  
<StructureSection load='2sgf' size='340' side='right'caption='[[2sgf]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2sgf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2SGF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2SGF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2sgf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2sgf OCA], [https://pdbe.org/2sgf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2sgf RCSB], [https://www.ebi.ac.uk/pdbsum/2sgf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2sgf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRTB_STRGR PRTB_STRGR] Has a primary specificity for large aliphatic or aromatic amino acids.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sg/2sgf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2sgf ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Proteinase 3D structures|Proteinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Meleagris gallopavo]]
[[Category: Meleagris gallopavo]]
[[Category: Protein complex]]
[[Category: Streptomyces griseus]]
[[Category: Streptogrisin B]]
[[Category: Anderson S]]
[[Category: Streptomyces chryseus]]
[[Category: Huang K]]
[[Category: Anderson, S.]]
[[Category: James MNG]]
[[Category: Huang, K.]]
[[Category: Laskowski Jr M]]
[[Category: James, M N.G.]]
[[Category: Lu W]]
[[Category: Jr., M Laskowski.]]
[[Category: Lu, W.]]
[[Category: PO4]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: protein inhibitor]]
[[Category: serine proteinase]]
 
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