2nu1: Difference between revisions

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<StructureSection load='2nu1' size='340' side='right'caption='[[2nu1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2nu1' size='340' side='right'caption='[[2nu1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Melga Melga] and [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NU1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NU1 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sgy|1sgy]], [[2sgf|2sgf]], [[3sgb|3sgb]], [[2nu0|2nu0]], [[2nu2|2nu2]], [[2nu3|2nu3]], [[2nu4|2nu4]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Streptogrisin_B Streptogrisin B], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.81 3.4.21.81] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu1 OCA], [https://pdbe.org/2nu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nu1 RCSB], [https://www.ebi.ac.uk/pdbsum/2nu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu1 OCA], [https://pdbe.org/2nu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nu1 RCSB], [https://www.ebi.ac.uk/pdbsum/2nu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PRTB_STRGR PRTB_STRGR]] Has a primary specificity for large aliphatic or aromatic amino acids.  
[https://www.uniprot.org/uniprot/PRTB_STRGR PRTB_STRGR] Has a primary specificity for large aliphatic or aromatic amino acids.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu1_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu1_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Melga]]
[[Category: Meleagris gallopavo]]
[[Category: Streptogrisin B]]
[[Category: Streptomyces griseus]]
[[Category: Streptomyces griseus]]
[[Category: Anderson, S]]
[[Category: Anderson S]]
[[Category: Bateman, K S]]
[[Category: Bateman KS]]
[[Category: Huang, K]]
[[Category: Huang K]]
[[Category: James, M N.G]]
[[Category: James MNG]]
[[Category: Laskowski, M]]
[[Category: Laskowski Jr M]]
[[Category: Lu, W]]
[[Category: Lu W]]
[[Category: Qasim, M A]]
[[Category: Qasim MA]]
[[Category: Aromatic p1 residue]]
[[Category: Enzyme-inhibitor complex]]
[[Category: Hydrolase]]

Latest revision as of 04:14, 21 November 2024

Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18IMolecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I

Structural highlights

2nu1 is a 2 chain structure with sequence from Meleagris gallopavo and Streptomyces griseus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRTB_STRGR Has a primary specificity for large aliphatic or aromatic amino acids.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2nu1, resolution 1.80Å

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OCA
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