2h6x: Difference between revisions

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[[Image:2h6x.jpg|left|200px]]<br /><applet load="2h6x" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2h6x, resolution 2.600&Aring;" />
'''Crystal Structure of Thioredoxin Wild Type in Hexagonal (p61) Space Group'''<br />


==About this Structure==
==Crystal Structure of Thioredoxin Wild Type in Hexagonal (p61) Space Group==
2H6X is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Lyase Lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.7.1.4 4.7.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H6X OCA].  
<StructureSection load='2h6x' size='340' side='right'caption='[[2h6x]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2h6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H6X FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h6x OCA], [https://pdbe.org/2h6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h6x RCSB], [https://www.ebi.ac.uk/pdbsum/2h6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h6x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/2h6x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h6x ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Lyase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Gavira JA]]
[[Category: Gavira, J.A.]]
[[Category: Godoy-Ruiz R]]
[[Category: Godoy-Ruiz, R.]]
[[Category: Ibarra-Molero B]]
[[Category: Ibarra-Molero, B.]]
[[Category: Sanchez-Ruiz JM]]
[[Category: Sanchez-Ruiz, J.M.]]
[[Category: MPD]]
[[Category: alpha beta]]
[[Category: electron transport]]
 
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