2fkb: Difference between revisions

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[[Image:2fkb.gif|left|200px]]


{{Structure
==Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12==
|PDB= 2fkb |SIZE=350|CAPTION= <scene name='initialview01'>2fkb</scene>, resolution 2.00&Aring;
<StructureSection load='2fkb' size='340' side='right'caption='[[2fkb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[2fkb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FKB FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04697 Nudix_Hydrolase_38], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK03759 PRK03759]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fkb OCA], [https://pdbe.org/2fkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fkb RCSB], [https://www.ebi.ac.uk/pdbsum/2fkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fkb ProSAT], [https://www.topsan.org/Proteins/MCSG/2fkb TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fkb OCA], [http://www.ebi.ac.uk/pdbsum/2fkb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fkb RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/YFCD_ECOLI YFCD_ECOLI]
 
== Evolutionary Conservation ==
'''Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fk/2fkb_consurf.spt"</scriptWhenChecked>
2FKB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKB OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Escherichia coli]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Edwards, A.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fkb ConSurf].
[[Category: Evdokimova, E.]]
<div style="clear:both"></div>
[[Category: Joachimiak, A.]]
__TOC__
[[Category: Kudritska, M.]]
</StructureSection>
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Escherichia coli K-12]]
[[Category: Nocek, B.]]
[[Category: Large Structures]]
[[Category: Savchenko, A.]]
[[Category: Edwards A]]
[[Category: escherichia coli k12]]
[[Category: Evdokimova E]]
[[Category: mad]]
[[Category: Joachimiak A]]
[[Category: mcsg]]
[[Category: Kudritska M]]
[[Category: midwest center for structural genomic]]
[[Category: Nocek B]]
[[Category: protein structure initiative]]
[[Category: Savchenko A]]
[[Category: psi]]
[[Category: putative nudix hydrolase]]
[[Category: putative protein]]
[[Category: structural genomic]]
 
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