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[[Image:2fkb.gif|left|200px]]<br /><applet load="2fkb" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2fkb, resolution 2.00&Aring;" />
'''Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12'''<br />


==About this Structure==
==Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12==
2FKB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKB OCA].
<StructureSection load='2fkb' size='340' side='right'caption='[[2fkb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Escherichia coli]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2fkb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FKB FirstGlance]. <br>
[[Category: Edwards, A.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Evdokimova, E.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Joachimiak, A.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fkb OCA], [https://pdbe.org/2fkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fkb RCSB], [https://www.ebi.ac.uk/pdbsum/2fkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fkb ProSAT], [https://www.topsan.org/Proteins/MCSG/2fkb TOPSAN]</span></td></tr>
[[Category: Kudritska, M.]]
</table>
[[Category: MCSG, Midwest Center for Structural Genomics.]]
== Function ==
[[Category: Nocek, B.]]
[https://www.uniprot.org/uniprot/YFCD_ECOLI YFCD_ECOLI]  
[[Category: Savchenko, A.]]
== Evolutionary Conservation ==
[[Category: ACT]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: GOL]]
Check<jmol>
[[Category: MG]]
  <jmolCheckbox>
[[Category: SO4]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fk/2fkb_consurf.spt"</scriptWhenChecked>
[[Category: escherichia coli k12]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: mad]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: mcsg]]
  </jmolCheckbox>
[[Category: midwest center for structural genomics]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fkb ConSurf].
[[Category: protein structure initiative]]
<div style="clear:both"></div>
[[Category: psi]]
__TOC__
[[Category: putative nudix hydrolase]]
</StructureSection>
[[Category: putative protein]]
[[Category: Escherichia coli K-12]]
[[Category: structural genomics]]
[[Category: Large Structures]]
 
[[Category: Edwards A]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:22:13 2008''
[[Category: Evdokimova E]]
[[Category: Joachimiak A]]
[[Category: Kudritska M]]
[[Category: Nocek B]]
[[Category: Savchenko A]]

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