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[[Image:2exr.gif|left|200px]]


{{Structure
==X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482==
|PDB= 2exr |SIZE=350|CAPTION= <scene name='initialview01'>2exr</scene>, resolution 1.702&Aring;
<StructureSection load='2exr' size='340' side='right'caption='[[2exr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Fad+Binding+Site+For+Residue+A+525'>AC1</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[2exr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EXR FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytokinin_dehydrogenase Cytokinin dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.99.12 1.5.99.12] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.702&#8491;</td></tr>
|GENE= CKX7, CKX5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam09265 Cytokin-bind], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam01565 FAD_binding_4]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2exr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2exr OCA], [https://pdbe.org/2exr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2exr RCSB], [https://www.ebi.ac.uk/pdbsum/2exr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2exr ProSAT], [https://www.topsan.org/Proteins/CESG/2exr TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2exr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2exr OCA], [http://www.ebi.ac.uk/pdbsum/2exr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2exr RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/CKX7_ARATH CKX7_ARATH] Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group (By similarity).
 
== Evolutionary Conservation ==
'''X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/2exr_consurf.spt"</scriptWhenChecked>
2EXR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXR OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2exr ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Cytokinin dehydrogenase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Bae E]]
[[Category: Bae, E.]]
[[Category: Bingman CA]]
[[Category: Bingman, C A.]]
[[Category: Bitto E]]
[[Category: Bitto, E.]]
[[Category: Han BW]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: Phillips Jr GN]]
[[Category: Han, B W.]]
[[Category: Wesenberg GE]]
[[Category: Jr., G N.Phillips.]]
[[Category: Wesenberg, G E.]]
[[Category: at5g21482 1]]
[[Category: center for eukaryotic structural genomic]]
[[Category: cesg]]
[[Category: ckx]]
[[Category: cytokinin oxidase/dehydrogenase]]
[[Category: oxidoreductase]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:55:11 2008''

Latest revision as of 12:06, 6 November 2024

X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482

Structural highlights

2exr is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.702Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

CKX7_ARATH Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2exr, resolution 1.70Å

Drag the structure with the mouse to rotate

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OCA
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