2dq3: Difference between revisions

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-[[Image:2dq3.png|left|200px]]
-{{STRUCTURE_2dq3|  PDB=2dq3  |  SCENE=  }}
+==Crystal structure of aq_298==
+<StructureSection load='2dq3' size='340' side='right'caption='[[2dq3]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-===Crystal structure of aq_298===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2dq3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DQ3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SSA:5-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE'>SSA</scene></td></tr>
-[[2dq3]] is a 2 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DQ3 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dq3 OCA], [https://pdbe.org/2dq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dq3 RCSB], [https://www.ebi.ac.uk/pdbsum/2dq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dq3 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dq3 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SYS_AQUAE SYS_AQUAE] Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dq/2dq3_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dq3 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
+*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
-[[Category: Aquifex aeolicus]]
+__TOC__
-[[Category: Serine--tRNA ligase]]
+</StructureSection>
-[[Category: Itoh, Y.]]
+[[Category: Aquifex aeolicus VF5]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Large Structures]]
-[[Category: Sekine, S.]]
+[[Category: Itoh Y]]
-[[Category: Yokoyama, S.]]
+[[Category: Sekine S]]
-[[Category: Coiled-coil]]
+[[Category: Yokoyama S]]
-[[Category: Homodimer]]
-[[Category: Ligase]]
-[[Category: National project on protein structural and functional analyse]]
-[[Category: Nppsfa]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]