2clv: Difference between revisions

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 <StructureSection load='2clv' size='340' side='right'caption='[[2clv]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2clv]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CLV FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2clv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CLV FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bqh|1bqh]], [[1fo0|1fo0]], [[1fzj|1fzj]], [[1fzk|1fzk]], [[1fzm|1fzm]], [[1fzo|1fzo]], [[1g6r|1g6r]], [[1g7p|1g7p]], [[1g7q|1g7q]], [[1kbg|1kbg]], [[1kj2|1kj2]], [[1kj3|1kj3]], [[1kpu|1kpu]], [[1kpv|1kpv]], [[1leg|1leg]], [[1lek|1lek]], [[1lk2|1lk2]], [[1mwa|1mwa]], [[1n59|1n59]], [[1nam|1nam]], [[1nan|1nan]], [[1osz|1osz]], [[1p1z|1p1z]], [[1p4l|1p4l]], [[1rjy|1rjy]], [[1rjz|1rjz]], [[1rk0|1rk0]], [[1rk1|1rk1]], [[1s7q|1s7q]], [[1s7r|1s7r]], [[1s7s|1s7s]], [[1s7t|1s7t]], [[1t0m|1t0m]], [[1t0n|1t0n]], [[1vac|1vac]], [[1vad|1vad]], [[1wbz|1wbz]], [[2ckb|2ckb]], [[2clz|2clz]], [[2mha|2mha]], [[2vaa|2vaa]], [[2vab|2vab]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2clv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clv OCA], [http://pdbe.org/2clv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2clv RCSB], [http://www.ebi.ac.uk/pdbsum/2clv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2clv ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2clv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clv OCA], [https://pdbe.org/2clv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2clv RCSB], [https://www.ebi.ac.uk/pdbsum/2clv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2clv ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/RBM5_MOUSE RBM5_MOUSE]] Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes production of a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes production of a catalytically active form of CASP2/Caspase-2 that induces apoptosis (By similarity). [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
+[https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 14: / Line 14: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/2clv_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 31: / Line 31: @@
 ==See Also==
 *[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
-*[[MHC 3D structures of MHC|MHC 3D structures of MHC]]
+*[[MHC 3D structures|MHC 3D structures]]
+*[[MHC I 3D structures|MHC I 3D structures]]
 == References ==
 <references/>
@@ Line 37: / Line 38: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Mus musculus]]
-[[Category: Auphan-Anezin, N]]
+[[Category: Auphan-Anezin N]]
-[[Category: Barrett-Wilt, G A]]
+[[Category: Barrett-Wilt GA]]
-[[Category: Guimezanes, A]]
+[[Category: Guimezanes A]]
-[[Category: Hunt, D F]]
+[[Category: Hunt DF]]
-[[Category: Malissen, B]]
+[[Category: Malissen B]]
-[[Category: Mazza, C]]
+[[Category: Mazza C]]
-[[Category: Montero-Julian, F]]
+[[Category: Montero-Julian F]]
-[[Category: Roussel, A]]
+[[Category: Roussel A]]
-[[Category: Schmitt-Verhulst, A M]]
+[[Category: Schmitt-Verhulst AM]]
-[[Category: Alloreactivity]]
-[[Category: Class i mhc]]
-[[Category: Glycoprotein]]
-[[Category: H-2kbm8]]
-[[Category: Immune response]]
-[[Category: Immune system]]
-[[Category: Immunoglobulin domain]]
-[[Category: Membrane]]
-[[Category: Mhc i]]
-[[Category: Polymorphism]]
-[[Category: Transmembrane]]