2aq3: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3==
==Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3==
<StructureSection load='2aq3' size='340' side='right' caption='[[2aq3]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2aq3' size='340' side='right'caption='[[2aq3]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2aq3]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQ3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2aq3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQ3 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2apb|2apb]], [[2apf|2apf]], [[2apt|2apt]], [[2apv|2apv]], [[2apw|2apw]], [[2apx|2apx]], [[2aq1|2aq1]], [[2aq2|2aq2]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq3 OCA], [https://pdbe.org/2aq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aq3 RCSB], [https://www.ebi.ac.uk/pdbsum/2aq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aq3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aq3 RCSB], [http://www.ebi.ac.uk/pdbsum/2aq3 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ENTC3_STAAU ENTC3_STAAU]] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aq3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aq3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aq3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[T-cell receptor|T-cell receptor]]
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Cho, S]]
[[Category: Cho S]]
[[Category: Guan, R]]
[[Category: Guan R]]
[[Category: Kerzic, M C]]
[[Category: Kerzic MC]]
[[Category: Kieke, M C]]
[[Category: Kieke MC]]
[[Category: Kranz, D M]]
[[Category: Kranz DM]]
[[Category: Mariuzza, R A]]
[[Category: Mariuzza RA]]
[[Category: Sundberg, E J]]
[[Category: Sundberg EJ]]
[[Category: Swaminathan, C P]]
[[Category: Swaminathan CP]]
[[Category: Yang, J]]
[[Category: Yang J]]
[[Category: Complex structure]]
[[Category: Immune system]]
[[Category: Staphlococcal enterotoxin c3]]
[[Category: T-cell receptor v beta domain]]

Latest revision as of 03:47, 21 November 2024

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3

Structural highlights

2aq3 is a 8 chain structure with sequence from Mus musculus and Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2aq3, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA