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[[Image:2aq2.gif|left|200px]]<br /><applet load="2aq2" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2aq2, resolution 1.800&Aring;" />
'''Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant'''<br />


==About this Structure==
==Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant==
2AQ2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA].  
<StructureSection load='2aq2' size='340' side='right'caption='[[2aq2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [https://pdbe.org/2aq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [https://www.ebi.ac.uk/pdbsum/2aq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aq2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TVB5_MOUSE TVB5_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aq2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aq2 ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
The nitty-gritty of protein interactions., Schreiber G, Structure. 2005 Dec;13(12):1737-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16338399 16338399]
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Cho, S.]]
[[Category: Cho S]]
[[Category: Guan, R.]]
[[Category: Guan R]]
[[Category: Kerzic, M C.]]
[[Category: Kerzic MC]]
[[Category: Kieke, M C.]]
[[Category: Kieke MC]]
[[Category: Kranz, D M.]]
[[Category: Kranz DM]]
[[Category: Mariuzza, R A.]]
[[Category: Mariuzza RA]]
[[Category: Sundberg, E J.]]
[[Category: Sundberg EJ]]
[[Category: Swaminathan, C P.]]
[[Category: Swaminathan CP]]
[[Category: Yang, J.]]
[[Category: Yang J]]
[[Category: NA]]
[[Category: SO4]]
[[Category: ZN]]
[[Category: complex structure]]
[[Category: staphlococcal enterotoxin c3]]
[[Category: t-cell receptor v beta domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:47 2008''

Latest revision as of 03:47, 21 November 2024

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutantCrystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant

Structural highlights

2aq2 is a 2 chain structure with sequence from Mus musculus and Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TVB5_MOUSE

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2aq2, resolution 1.80Å

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