2aeo: Difference between revisions

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[[Image:2aeo.png|left|200px]]


{{STRUCTURE_2aeo|  PDB=2aeo  |  SCENE=  }}
==Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase==
 
<StructureSection load='2aeo' size='340' side='right'caption='[[2aeo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2aeo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AEO FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[2aeo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEO OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aeo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aeo OCA], [https://pdbe.org/2aeo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aeo RCSB], [https://www.ebi.ac.uk/pdbsum/2aeo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aeo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SODC_BOVIN SODC_BOVIN] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ae/2aeo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aeo ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Superoxide Dismutase|Superoxide Dismutase]]
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016416478</ref><ref group="xtra">PMID:011749487</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Superoxide dismutase]]
[[Category: Large Structures]]
[[Category: Calderone, V.]]
[[Category: Calderone V]]
[[Category: Casini, A.]]
[[Category: Casini A]]
[[Category: Mangani, S.]]
[[Category: Mangani S]]
[[Category: Messori, L.]]
[[Category: Messori L]]
[[Category: Orioli, P L.]]
[[Category: Orioli PL]]
[[Category: Cancer]]
[[Category: Cisplatin]]
[[Category: Cu]]
[[Category: Metal based drug]]
[[Category: Oxidoreductase]]
[[Category: Platinum]]
[[Category: Protein]]
[[Category: Sod]]
[[Category: Zn sod]]

Latest revision as of 10:48, 30 October 2024

Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutaseCrystal structure of cisplatinated bovine Cu,Zn superoxide dismutase

Structural highlights

2aeo is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SODC_BOVIN Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2aeo, resolution 1.80Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA