1yp9: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1yp9.gif|left|200px]]<br /><applet load="1yp9" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1yp9, resolution 2.10&Aring;" />
-'''Trypsin Inhibitor Complex'''<br />
-==About this Structure==
+==Trypsin Inhibitor Complex==
-YP9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with CA, UIZ and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YP9 OCA].
+<StructureSection load='1yp9' size='340' side='right'caption='[[1yp9]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1yp9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YP9 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UIZ:(1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YLMETHYL)-1-BENZYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROZILIN-4-YL-BENZAMIDINE'>UIZ</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yp9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp9 OCA], [https://pdbe.org/1yp9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yp9 RCSB], [https://www.ebi.ac.uk/pdbsum/1yp9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yp9 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1yp9_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yp9 ConSurf].
+<div style="clear:both"></div>
-==Reference==
+==See Also==
-A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates., Fokkens J, Klebe G, Angew Chem Int Ed Engl. 2006 Jan 30;45(6):985-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16374786 16374786]
+*[[Trypsin 3D structures|Trypsin 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Bos taurus]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Trypsin]]
+[[Category: Diederich F]]
-[[Category: Diederich, F.]]
+[[Category: Fokkens J]]
-[[Category: Fokkens, J.]]
+[[Category: Heine A]]
-[[Category: Heine, A.]]
+[[Category: Klebe G]]
-[[Category: Klebe, G.]]
+[[Category: Obst-Sander U]]
-[[Category: Obst-Sander, U.]]
-[[Category: CA]]
-[[Category: GOL]]
-[[Category: UIZ]]
-[[Category: 6 stranded beta-sheet]]
-[[Category: barrel]]
-[[Category: inhibitor complex]]
-[[Category: trypsin]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 06:57:51 2007''