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[[Image:1vp7.gif|left|200px]]


{{Structure
==Crystal structure of Exodeoxyribonuclease VII small subunit (NP_881400.1) from Bordetella pertussis at 2.40 A resolution==
|PDB= 1vp7 |SIZE=350|CAPTION= <scene name='initialview01'>1vp7</scene>, resolution 2.40&Aring;
<StructureSection load='1vp7' size='340' side='right'caption='[[1vp7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[1vp7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bordetella_pertussis_Tohama_I Bordetella pertussis Tohama I]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VP7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VP7 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_VII Exodeoxyribonuclease VII], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.6 3.1.11.6] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
|GENE= NP_881400.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=257313 Bordetella pertussis Tohama I])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00977 PRK00977]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vp7 OCA], [https://pdbe.org/1vp7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vp7 RCSB], [https://www.ebi.ac.uk/pdbsum/1vp7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vp7 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vp7 TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vp7 OCA], [http://www.ebi.ac.uk/pdbsum/1vp7 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vp7 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/EX7S_BORPE EX7S_BORPE] Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.[HAMAP-Rule:MF_00337]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/1vp7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vp7 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of Exodeoxyribonuclease VII small subunit (NP_881400.1) from Bordetella pertussis at 2.40 A resolution'''
==See Also==
 
*[[Exonuclease 3D structures|Exonuclease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1VP7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bordetella_pertussis_tohama_i Bordetella pertussis tohama i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VP7 OCA].
[[Category: Bordetella pertussis Tohama I]]
[[Category: Bordetella pertussis tohama i]]
[[Category: Large Structures]]
[[Category: Exodeoxyribonuclease VII]]
[[Category: Single protein]]
[[Category: JCSG, Joint Center for Structural Genomics.]]
[[Category: exodeoxyribonuclease vii small subunit e c.3 1.11 6]]
[[Category: jcsg]]
[[Category: joint center for structural genomic]]
[[Category: np_881400 1]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:26:50 2008''

Latest revision as of 03:36, 21 November 2024

Crystal structure of Exodeoxyribonuclease VII small subunit (NP_881400.1) from Bordetella pertussis at 2.40 A resolutionCrystal structure of Exodeoxyribonuclease VII small subunit (NP_881400.1) from Bordetella pertussis at 2.40 A resolution

Structural highlights

1vp7 is a 6 chain structure with sequence from Bordetella pertussis Tohama I. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

EX7S_BORPE Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.[HAMAP-Rule:MF_00337]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1vp7, resolution 2.40Å

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