1vds: Difference between revisions

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New page: left|200px<br /><applet load="1vds" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vds, resolution 1.60Å" /> '''The crystal structur...
 
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[[Image:1vds.jpg|left|200px]]<br /><applet load="1vds" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1vds, resolution 1.60&Aring;" />
'''The crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in space'''<br />


==About this Structure==
==The crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in space==
1VDS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VDS OCA].  
<StructureSection load='1vds' size='340' side='right'caption='[[1vds]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1vds]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VDS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vds OCA], [https://pdbe.org/1vds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vds RCSB], [https://www.ebi.ac.uk/pdbsum/1vds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vds ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/1vds_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vds ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Aibara S]]
[[Category: Aibara, S.]]
[[Category: DeLucas LJ]]
[[Category: DeLucas, L.J.]]
[[Category: Hirose M]]
[[Category: Hirose, M.]]
[[Category: Kidera A]]
[[Category: Kidera, A.]]
[[Category: Shibata K]]
[[Category: Shibata, K.]]
[[Category: Suzuki A]]
[[Category: Suzuki, A.]]
[[Category: Yamane T]]
[[Category: Yamane, T.]]
[[Category: hen egg white]]
[[Category: lysozyme]]
[[Category: microgravity]]
[[Category: tetragonal]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 04:45:42 2007''

Latest revision as of 10:33, 30 October 2024

The crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in spaceThe crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in space

Structural highlights

1vds is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LYSC_CHICK Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

1vds, resolution 1.60Å

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