1vat: Difference between revisions

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-[[Image:1vat.gif|left|200px]]
- {{Structure
+==Iodine derivative of hen egg-white lysozyme==
-|PDB= 1vat |SIZE=350|CAPTION= <scene name='initialview01'>1vat</scene>, resolution 1.6&Aring;
+<StructureSection load='1vat' size='340' side='right'caption='[[1vat]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>
+<table><tr><td colspan='2'>[[1vat]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VAT FirstGlance]. <br>
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
-|DOMAIN=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vat OCA], [https://pdbe.org/1vat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vat RCSB], [https://www.ebi.ac.uk/pdbsum/1vat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vat ProSAT], [https://www.topsan.org/Proteins/RSGI/1vat TOPSAN]</span></td></tr>
-|RELATEDENTRY=[[1vau|1VAU]]
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vat OCA], [http://www.ebi.ac.uk/pdbsum/1vat PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vat RCSB]</span>
+== Function ==
-}}
+[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/1vat_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vat ConSurf].
+<div style="clear:both"></div>
-'''Iodine derivative of hen egg-white lysozyme'''
+==See Also==
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-VAT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAT OCA].
+__TOC__
+</StructureSection>
 [[Category: Gallus gallus]]
-[[Category: Lysozyme]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Kamiya N]]
-[[Category: Kamiya, N.]]
+[[Category: Kawamoto M]]
-[[Category: Kawamoto, M.]]
+[[Category: Miki K]]
-[[Category: Miki, K.]]
+[[Category: Miyatake H]]
-[[Category: Miyatake, H.]]
+[[Category: Park SY]]
-[[Category: Park, S Y.]]
+[[Category: Takeda K]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
-[[Category: Takeda, K.]]
-[[Category: iodine-derivative]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:21:55 2008''