1ufr: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1ufr.gif|left|200px]]


{{Structure
==Crystal Structure of TT1027 from Thermus thermophilus HB8==
|PDB= 1ufr |SIZE=350|CAPTION= <scene name='initialview01'>1ufr</scene>, resolution 2.60&Aring;
<StructureSection load='1ufr' size='340' side='right'caption='[[1ufr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[1ufr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UFR FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ufr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufr OCA], [https://pdbe.org/1ufr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ufr RCSB], [https://www.ebi.ac.uk/pdbsum/1ufr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ufr ProSAT], [https://www.topsan.org/Proteins/RSGI/1ufr TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ufr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufr OCA], [http://www.ebi.ac.uk/pdbsum/1ufr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ufr RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/PYRR_THET8 PYRR_THET8] Probably regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. In contrast to pyr attenuation in Bacillus, PyrR from Thermus could act as a translational repressor: the binding of PyrR at its proposed recognition site in the transcript would prevent initiation of translation of the leader peptide, resulting in terminator formation and reduced expression of downstream genes (By similarity). Also displays uracil phosphoribosyltransferase activity (By similarity).
 
== Evolutionary Conservation ==
'''Crystal Structure of TT1027 from Thermus thermophilus HB8'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufr_consurf.spt"</scriptWhenChecked>
1UFR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFR OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ufr ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Kuramitsu, S.]]
[[Category: Kuramitsu S]]
[[Category: Matsuura, T.]]
[[Category: Matsuura T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Sakai H]]
[[Category: Sakai, H.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Terada T]]
[[Category: Terada, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: pyrimidine nucleotide biosynthesis]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rna-binding protein]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcriptional attenuation]]
[[Category: uracil phosphoribosyltransferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:09:43 2008''

Latest revision as of 03:33, 21 November 2024

Crystal Structure of TT1027 from Thermus thermophilus HB8Crystal Structure of TT1027 from Thermus thermophilus HB8

Structural highlights

1ufr is a 4 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PYRR_THET8 Probably regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. In contrast to pyr attenuation in Bacillus, PyrR from Thermus could act as a translational repressor: the binding of PyrR at its proposed recognition site in the transcript would prevent initiation of translation of the leader peptide, resulting in terminator formation and reduced expression of downstream genes (By similarity). Also displays uracil phosphoribosyltransferase activity (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1ufr, resolution 2.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1ufr&oldid=4200966"