1tkf: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1tkf.gif|left|200px]]
- {{Structure
+==Streptomyces griseus aminopeptidase complexed with D-tryptophan==
-|PDB= 1tkf |SIZE=350|CAPTION= <scene name='initialview01'>1tkf</scene>, resolution 1.20&Aring;
+<StructureSection load='1tkf' size='340' side='right'caption='[[1tkf]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>
+<table><tr><td colspan='2'>[[1tkf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TKF FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tkf OCA], [https://pdbe.org/1tkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tkf RCSB], [https://www.ebi.ac.uk/pdbsum/1tkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tkf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/APX_STRGG APX_STRGG] An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).<ref>PMID:2503378</ref> <ref>PMID:8444149</ref> <ref>PMID:8665903</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tk/1tkf_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tkf ConSurf].
+<div style="clear:both"></div>
-'''Streptomyces griseus aminopeptidase complexed with D-tryptophan'''
+==See Also==
+*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
+*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
-==About this Structure==
+== References ==
-TKF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TKF OCA].
+<references/>
-[[Category: Single protein]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Streptomyces griseus]]
-[[Category: Blumberg, S.]]
+[[Category: Blumberg S]]
-[[Category: Gilboa, R.]]
+[[Category: Gilboa R]]
-[[Category: Reiland, V.]]
+[[Category: Reiland V]]
-[[Category: Schomburg, D.]]
+[[Category: Schomburg D]]
-[[Category: Shoham, G.]]
+[[Category: Shoham G]]
-[[Category: Shoham, Y.]]
+[[Category: Shoham Y]]
-[[Category: Spungin-Bialik, A.]]
+[[Category: Spungin-Bialik A]]
-[[Category: CA]]
-[[Category: DTR]]
-[[Category: ZN]]
-[[Category: calcium activation]]
-[[Category: double-zinc metalloproteinase]]
-[[Category: protein-inhibitor complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:19:34 2008''