1sqx: Difference between revisions

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==Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A==
==Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A==
<StructureSection load='1sqx' size='340' side='right' caption='[[1sqx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='1sqx' size='340' side='right'caption='[[1sqx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1sqx]] is a 11 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SQX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1sqx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SQX FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SMA:STIGMATELLIN+A'>SMA</scene>, <scene name='pdbligand=UQ2:UBIQUINONE-2'>UQ2</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qcr|1qcr]], [[1l0l|1l0l]], [[1sqv|1sqv]], [[1sqb|1sqb]], [[1sqp|1sqp]], [[1sqq|1sqq]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SMA:STIGMATELLIN+A'>SMA</scene>, <scene name='pdbligand=UQ2:UBIQUINONE-2'>UQ2</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquinol--cytochrome-c_reductase Ubiquinol--cytochrome-c reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.2.2 1.10.2.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sqx OCA], [https://pdbe.org/1sqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sqx RCSB], [https://www.ebi.ac.uk/pdbsum/1sqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sqx ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sqx RCSB], [http://www.ebi.ac.uk/pdbsum/1sqx PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/QCR8_BOVIN QCR8_BOVIN] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sqx_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sqx_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sqx ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1sqx" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Cytochrome bc1 complex|Cytochrome bc1 complex]]
*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
*[[Cytochrome c|Cytochrome c]]
*[[Cytochrome bc1 3D structures|Cytochrome bc1 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Ubiquinol--cytochrome-c reductase]]
[[Category: Large Structures]]
[[Category: Elberry, M.]]
[[Category: Elberry M]]
[[Category: Esser, L.]]
[[Category: Esser L]]
[[Category: Li, Y F.]]
[[Category: Li YF]]
[[Category: Quinn, B.]]
[[Category: Quinn B]]
[[Category: Xia, D.]]
[[Category: Xia D]]
[[Category: Yu, C A.]]
[[Category: Yu CA]]
[[Category: Yu, L.]]
[[Category: Yu L]]
[[Category: Zhang, M.]]
[[Category: Zhang M]]
[[Category: Cytochrome bc1]]
[[Category: Electron transport]]
[[Category: Membrane protein]]
[[Category: Oxidoreductase]]
[[Category: Qo inhibitor]]

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