1rhd: Difference between revisions

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[[Image:1rhd.gif|left|200px]]


{{Structure
==STRUCTURE OF BOVINE LIVER RHODANESE. I. STRUCTURE DETERMINATION AT 2.5 ANGSTROMS RESOLUTION AND A COMPARISON OF THE CONFORMATION AND SEQUENCE OF ITS TWO DOMAINS==
|PDB= 1rhd |SIZE=350|CAPTION= <scene name='initialview01'>1rhd</scene>, resolution 2.5&Aring;
<StructureSection load='1rhd' size='340' side='right'caption='[[1rhd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=S:SULFUR ATOM'>S</scene>
<table><tr><td colspan='2'>[[1rhd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RHD FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thiosulfate_sulfurtransferase Thiosulfate sulfurtransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.1 2.8.1.1]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rhd OCA], [https://pdbe.org/1rhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rhd RCSB], [https://www.ebi.ac.uk/pdbsum/1rhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rhd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THTR_BOVIN THTR_BOVIN] Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (By similarity). Formation of iron-sulfur complexes and cyanide detoxification. Binds molecular oxygen and sulfur.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/1rhd_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rhd ConSurf].
<div style="clear:both"></div>


'''STRUCTURE OF BOVINE LIVER RHODANESE. I. STRUCTURE DETERMINATION AT 2.5 ANGSTROMS RESOLUTION AND A COMPARISON OF THE CONFORMATION AND SEQUENCE OF ITS TWO DOMAINS'''
==See Also==
 
*[[Sulfurtransferase|Sulfurtransferase]]
 
__TOC__
==About this Structure==
</StructureSection>
1RHD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHD OCA].
 
==Reference==
Structure of bovine liver rhodanese. I. Structure determination at 2.5 A resolution and a comparison of the conformation and sequence of its two domains., Ploegman JH, Drent G, Kalk KH, Hol WG, J Mol Biol. 1978 Aug 25;123(4):557-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/691057 691057]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Thiosulfate sulfurtransferase]]
[[Category: Drent G]]
[[Category: Drent, G.]]
[[Category: Hol WGJ]]
[[Category: Hol, W G.J.]]
[[Category: Kalk KH]]
[[Category: Kalk, K H.]]
[[Category: Ploegman JH]]
[[Category: Ploegman, J H.]]
[[Category: S]]
[[Category: cyanide sulfur)]]
[[Category: transferase(thiosulfate]]
 
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