1r8h: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 3: / Line 3: @@
 <StructureSection load='1r8h' size='340' side='right'caption='[[1r8h]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1r8h]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpv6a Hpv6a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8H OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1R8H FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1r8h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_papillomavirus_type_6a Human papillomavirus type 6a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R8H FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">E2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=37122 HPV6A])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1r8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8h OCA], [http://pdbe.org/1r8h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1r8h RCSB], [http://www.ebi.ac.uk/pdbsum/1r8h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8h ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8h OCA], [https://pdbe.org/1r8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r8h RCSB], [https://www.ebi.ac.uk/pdbsum/1r8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8h ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/VE2_HPV6A VE2_HPV6A]] E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.
+[https://www.uniprot.org/uniprot/VE2_HPV6A VE2_HPV6A] E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 15: / Line 15: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/1r8h_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 29: / Line 29: @@
 </div>
 <div class="pdbe-citations 1r8h" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Regulatory protein E2|Regulatory protein E2]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Hpv6a]]
+[[Category: Human papillomavirus type 6a]]
 [[Category: Large Structures]]
-[[Category: Brady, R L]]
+[[Category: Brady RL]]
-[[Category: Dell, G]]
+[[Category: Dell G]]
-[[Category: Gaston, K]]
+[[Category: Gaston K]]
-[[Category: Parish, J]]
+[[Category: Parish J]]
-[[Category: Tranter, R]]
+[[Category: Tranter R]]
-[[Category: Wilkinson, K W]]
+[[Category: Wilkinson KW]]
-[[Category: Anti-parallel beta-barrel]]
-[[Category: Dna-binding domain]]
-[[Category: Replication]]
-[[Category: Transcription]]