1q7j: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1q7j.jpg|left|200px]]<br /><applet load="1q7j" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1q7j" />
-'''Structural Analysis of Integrin alpha IIb beta 3- Disintegrin with the AKGDWN Motif'''<br />
-==About this Structure==
+==Structural Analysis of Integrin alpha IIb beta 3- Disintegrin with the AKGDWN Motif==
-Q7J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1Q7J OCA].
+<StructureSection load='1q7j' size='340' side='right'caption='[[1q7j]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1q7j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q7J FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q7j OCA], [https://pdbe.org/1q7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q7j RCSB], [https://www.ebi.ac.uk/pdbsum/1q7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q7j ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q7/1q7j_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q7j ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Disintegrin|Disintegrin]]
+__TOC__
+</StructureSection>
 [[Category: Calloselasma rhodostoma]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Chen, C.Y.]]
+[[Category: Chen CY]]
-[[Category: Chen, Y.C.]]
+[[Category: Chen YC]]
-[[Category: Chuang, W.J.]]
+[[Category: Chuang WJ]]
-[[Category: Shiu, J.H.]]
+[[Category: Shiu JH]]
-[[Category: disintegrin]]
-[[Category: integrin]]
-[[Category: nmr]]
-[[Category: rhodostomin]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 00:27:20 2007''