1osy: Difference between revisions
No edit summary |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of FIP-Fve fungal immunomodulatory protein== | ==Crystal structure of FIP-Fve fungal immunomodulatory protein== | ||
<StructureSection load='1osy' size='340' side='right' caption='[[1osy]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='1osy' size='340' side='right'caption='[[1osy]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1osy]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1osy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Flammulina_velutipes Flammulina velutipes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OSY FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr><td class="sblockLbl"><b>[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1osy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1osy OCA], [https://pdbe.org/1osy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1osy RCSB], [https://www.ebi.ac.uk/pdbsum/1osy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1osy ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/FVE_FLAVE FVE_FLAVE] Lectin with specificity for complex cell-surface carbohydrates. Possesses immunomodulatory activity, stimulates lymphocyte mitogenesis, suppresses systemic anaphylaxis reactions and edema, enhances transcription of IL-2, IFN-gamma and TNF-alpha and hemagglutinates red blood cells. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 15: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 1osy" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 20: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Flammulina velutipes]] | [[Category: Flammulina velutipes]] | ||
[[Category: Chua | [[Category: Large Structures]] | ||
[[Category: Joseph | [[Category: Chua KY]] | ||
[[Category: Kolatkar | [[Category: Joseph JS]] | ||
[[Category: Palasingam | [[Category: Kolatkar PR]] | ||
[[Category: Robinson | [[Category: Palasingam P]] | ||
[[Category: Seow | [[Category: Robinson H]] | ||
[[Category: Shai | [[Category: Seow SV]] | ||
[[Category: Shai V]] | |||