1nri: Difference between revisions

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New page: left|200px<br /><applet load="1nri" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nri, resolution 1.90Å" /> '''Crystal Structure of...
 
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[[Image:1nri.gif|left|200px]]<br /><applet load="1nri" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1nri, resolution 1.90&Aring;" />
'''Crystal Structure of Putative Phosphosugar Isomerase HI0754 from Haemophilus influenzae'''<br />


==About this Structure==
==Crystal Structure of Putative Phosphosugar Isomerase HI0754 from Haemophilus influenzae==
1NRI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NRI OCA].  
<StructureSection load='1nri' size='340' side='right'caption='[[1nri]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1nri]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NRI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nri OCA], [https://pdbe.org/1nri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nri RCSB], [https://www.ebi.ac.uk/pdbsum/1nri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nri ProSAT], [https://www.topsan.org/Proteins/MCSG/1nri TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MURQ_HAEIN MURQ_HAEIN] Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/1nri_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nri ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak A]]
[[Category: Kim, Y.]]
[[Category: Kim Y]]
[[Category: MCSG, Midwest.Center.for.Structural.Genomics.]]
[[Category: Ng R]]
[[Category: Ng, R.]]
[[Category: Quartey P]]
[[Category: Quartey, P.]]
[[Category: Zarembinski TI]]
[[Category: Zarembinski, T.I.]]
[[Category: haemophilus influenzae]]
[[Category: hypothetical protein]]
[[Category: mcsg]]
[[Category: midwest center for structural genomics]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 22:30:25 2007''

Latest revision as of 10:05, 30 October 2024

Crystal Structure of Putative Phosphosugar Isomerase HI0754 from Haemophilus influenzaeCrystal Structure of Putative Phosphosugar Isomerase HI0754 from Haemophilus influenzae

Structural highlights

1nri is a 1 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

MURQ_HAEIN Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1nri, resolution 1.90Å

Drag the structure with the mouse to rotate

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OCA
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