1n10: Difference between revisions

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==Crystal Structure of Phl p 1, a Major Timothy Grass Pollen Allergen==
==Crystal Structure of Phl p 1, a Major Timothy Grass Pollen Allergen==
<StructureSection load='1n10' size='340' side='right' caption='[[1n10]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='1n10' size='340' side='right'caption='[[1n10]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1n10]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Phleum_pratense Phleum pratense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N10 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N10 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1n10]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Phleum_pratense Phleum pratense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N10 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHLPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=15957 Phleum pratense])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n10 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1n10 RCSB], [http://www.ebi.ac.uk/pdbsum/1n10 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1n10 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n10 OCA], [https://pdbe.org/1n10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n10 RCSB], [https://www.ebi.ac.uk/pdbsum/1n10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n10 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1n10 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPAP1_PHLPR MPAP1_PHLPR]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n10_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n10_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n10 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Phleum pratense]]
[[Category: Phleum pratense]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Ball, T]]
[[Category: Ball T]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Fedorov, A A]]
[[Category: Fedorov AA]]
[[Category: Leistler, B]]
[[Category: Leistler B]]
[[Category: Structural genomic]]
[[Category: Valenta R]]
[[Category: Valenta, R]]
[[Category: Allergen]]
[[Category: Double-psi beta barrel]]
[[Category: Expansin]]
[[Category: Immunoglobulin-like fold]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Phl p 1]]
[[Category: Plant allergen]]
[[Category: PSI, Protein structure initiative]]

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