1mbk: Difference between revisions

No edit summary
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:


==MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3==
==MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3==
<StructureSection load='1mbk' size='340' side='right'caption='[[1mbk]], [[NMR_Ensembles_of_Models | 50 NMR models]]' scene=''>
<StructureSection load='1mbk' size='340' side='right'caption='[[1mbk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mbk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MBK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mbk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MBK FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 50 models</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mbj|1mbj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mbk OCA], [http://pdbe.org/1mbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1mbk RCSB], [http://www.ebi.ac.uk/pdbsum/1mbk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1mbk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mbk OCA], [https://pdbe.org/1mbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mbk RCSB], [https://www.ebi.ac.uk/pdbsum/1mbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mbk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE]] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.  
[https://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 15: Line 15:
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mbk_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mbk_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
Line 31: Line 31:


==See Also==
==See Also==
*[[Transcriptional activator|Transcriptional activator]]
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 38: Line 38:
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Aimoto, S]]
[[Category: Aimoto S]]
[[Category: Ametani, Y]]
[[Category: Ametani Y]]
[[Category: Hirata, Z]]
[[Category: Hirata Z]]
[[Category: Hojo, H]]
[[Category: Hojo H]]
[[Category: Ishii, S]]
[[Category: Ishii S]]
[[Category: Morikawa, S]]
[[Category: Morikawa S]]
[[Category: Nakamura, H]]
[[Category: Nakamura H]]
[[Category: Nishimura, Y]]
[[Category: Nishimura Y]]
[[Category: Ogata, K]]
[[Category: Ogata K]]
[[Category: Sarai, A]]
[[Category: Sarai A]]
[[Category: Yoshimura, S]]
[[Category: Yoshimura S]]
[[Category: Zhang, R]]
[[Category: Zhang R]]
[[Category: Dna binding protein]]
[[Category: Protooncogene product]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA