1l2g: Difference between revisions
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<StructureSection load='1l2g' size='340' side='right'caption='[[1l2g]], [[Resolution|resolution]] 2.85Å' scene=''> | <StructureSection load='1l2g' size='340' side='right'caption='[[1l2g]], [[Resolution|resolution]] 2.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1l2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1l2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L2G FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å, 2 models</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l2g OCA], [https://pdbe.org/1l2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l2g RCSB], [https://www.ebi.ac.uk/pdbsum/1l2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l2g ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l2g OCA], [https://pdbe.org/1l2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l2g RCSB], [https://www.ebi.ac.uk/pdbsum/1l2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l2g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/GD_HHV1P GD_HHV1P] Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM, PVRL1 and 3-O-sulfated heparan sulfate. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l2/1l2g_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l2/1l2g_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human alphaherpesvirus 1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Carfi | [[Category: Carfi A]] | ||
[[Category: Cohen | [[Category: Cohen GH]] | ||
[[Category: Eisenberg | [[Category: Eisenberg RJ]] | ||
[[Category: Krummenacher | [[Category: Krummenacher C]] | ||
[[Category: Whitbeck | [[Category: Whitbeck JC]] | ||
[[Category: Wiley | [[Category: Wiley DC]] | ||
[[Category: Willis | [[Category: Willis SH]] | ||