3ldh: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:3ldh.png|left|200px]]
-<!--
+==A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes==
-The line below this paragraph, containing "STRUCTURE_3ldh", creates the "Structure Box" on the page.
+<StructureSection load='3ldh' size='340' side='right'caption='[[3ldh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3ldh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. The June 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Lactate Dehydrogenase''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_6 10.2210/rcsb_pdb/mom_2008_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LDH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LDH FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
-{{STRUCTURE_3ldh|  PDB=3ldh  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ldh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ldh OCA], [https://pdbe.org/3ldh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ldh RCSB], [https://www.ebi.ac.uk/pdbsum/3ldh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ldh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LDHA_SQUAC LDHA_SQUAC]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ld/3ldh_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ldh ConSurf].
+<div style="clear:both"></div>
-'''A COMPARISON OF THE STRUCTURES OF APO DOGFISH M4 LACTATE DEHYDROGENASE AND ITS TERNARY COMPLEXES'''
+==See Also==
+*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
+__TOC__
-{{ABSTRACT_940154}}
+</StructureSection>
+[[Category: Lactate Dehydrogenase]]
-==About this Structure==
+[[Category: Large Structures]]
-LDH is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LDH OCA].
+[[Category: RCSB PDB Molecule of the Month]]
-[[Category: L-lactate dehydrogenase]]
+[[Category: Squalus acanthias]]
-[[Category: Single protein]]
+[[Category: Adams MJ]]
-[[Category: Adams, M J.]]
+[[Category: Buehner M]]
-[[Category: Buehner, M.]]
+[[Category: Ford GC]]
-[[Category: Ford, G C.]]
+[[Category: Hackert ML]]
-[[Category: Hackert, M L.]]
+[[Category: Lentzjunior PJ]]
-[[Category: Lentzjunior, P J.]]
+[[Category: Rossmann MG]]
-[[Category: Rossmann, M G.]]
+[[Category: Smiley IE]]
-[[Category: Smiley, I E.]]
+[[Category: Steindel SJ]]
-[[Category: Steindel, S J.]]
+[[Category: White JL]]
-[[Category: White, J L.]]
-[[Category: Choh donor]]
-[[Category: Nad acceptr]]
-[[Category: Oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 18:27:22 2008''