3ldh: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3ldh.png|left|200px]]


{{STRUCTURE_3ldh|  PDB=3ldh  |  SCENE=  }}
==A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes==
 
<StructureSection load='3ldh' size='340' side='right'caption='[[3ldh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ldh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. The June 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Lactate Dehydrogenase''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_6 10.2210/rcsb_pdb/mom_2008_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LDH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LDH FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
[[3ldh]] is a 1 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. The June 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Lactate Dehydrogenase''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_6 10.2210/rcsb_pdb/mom_2008_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LDH OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ldh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ldh OCA], [https://pdbe.org/3ldh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ldh RCSB], [https://www.ebi.ac.uk/pdbsum/3ldh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ldh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDHA_SQUAC LDHA_SQUAC]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ld/3ldh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ldh ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:000940154</ref><references group="xtra"/>
[[Category: L-lactate dehydrogenase]]
[[Category: Lactate Dehydrogenase]]
[[Category: Lactate Dehydrogenase]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Squalus acanthias]]
[[Category: Squalus acanthias]]
[[Category: Adams, M J.]]
[[Category: Adams MJ]]
[[Category: Buehner, M.]]
[[Category: Buehner M]]
[[Category: Ford, G C.]]
[[Category: Ford GC]]
[[Category: Hackert, M L.]]
[[Category: Hackert ML]]
[[Category: Lentzjunior, P J.]]
[[Category: Lentzjunior PJ]]
[[Category: Rossmann, M G.]]
[[Category: Rossmann MG]]
[[Category: Smiley, I E.]]
[[Category: Smiley IE]]
[[Category: Steindel, S J.]]
[[Category: Steindel SJ]]
[[Category: White, J L.]]
[[Category: White JL]]
[[Category: Choh donor]]
[[Category: Nad acceptor]]
[[Category: Oxidoreductase]]

Latest revision as of 12:23, 30 October 2024

A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexesA comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes

Structural highlights

3ldh is a 1 chain structure with sequence from Squalus acanthias. The June 2008 RCSB PDB Molecule of the Month feature on Lactate Dehydrogenase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2008_6. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LDHA_SQUAC

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3ldh, resolution 3.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3ldh&oldid=4199337"