5ldh: Difference between revisions

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-[[Image:5ldh.png|left|200px]]
-{{STRUCTURE_5ldh|  PDB=5ldh  |  SCENE=  }}
+==STRUCTURE OF THE ACTIVE TERNARY COMPLEX OF PIG HEART LACTATE DEHYDROGENASE WITH S-LAC-NAD AT 2.7 ANGSTROMS RESOLUTION==
+<StructureSection load='5ldh' size='340' side='right'caption='[[5ldh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-===STRUCTURE OF THE ACTIVE TERNARY COMPLEX OF PIG HEART LACTATE DEHYDROGENASE WITH S-LAC-NAD AT 2.7 ANGSTROMS RESOLUTION===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ldh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LDH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LDH FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LNC:(3S)-5-(3-CARBOXY-3-HYDROXYPROPYL)+NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>LNC</scene></td></tr>
-[[5ldh]] is a 2 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LDH OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ldh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ldh OCA], [https://pdbe.org/5ldh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ldh RCSB], [https://www.ebi.ac.uk/pdbsum/5ldh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ldh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LDHB_PIG LDHB_PIG]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ld/5ldh_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=5ldh ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
+*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:007338899</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: L-lactate dehydrogenase]]
 [[Category: Sus scrofa]]
-[[Category: Grau, U M.]]
+[[Category: Grau UM]]
-[[Category: Rossmann, M G.]]
+[[Category: Rossmann MG]]
-[[Category: Choh donor]]
-[[Category: Nad acceptr]]
-[[Category: Oxidoreductase]]