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[[Image:1jev.jpg|left|200px]]<br /><applet load="1jev" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1jev, resolution 1.3&Aring;" />
'''OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KWK'''<br />


==About this Structure==
==OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KWK==
1JEV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=IUM:'>IUM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JEV OCA].  
<StructureSection load='1jev' size='340' side='right'caption='[[1jev]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1jev]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JEV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jev OCA], [https://pdbe.org/1jev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jev RCSB], [https://www.ebi.ac.uk/pdbsum/1jev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jev ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1jev_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jev ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
The role of water in sequence-independent ligand binding by an oligopeptide transporter protein., Tame JR, Sleigh SH, Wilkinson AJ, Ladbury JE, Nat Struct Biol. 1996 Dec;3(12):998-1001. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8946852 8946852]
*[[ABC transporter 3D structures|ABC transporter 3D structures]]
[[Category: Salmonella typhimurium]]
__TOC__
[[Category: Single protein]]
</StructureSection>
[[Category: Tame, J.]]
[[Category: Large Structures]]
[[Category: Wilkinson, A J.]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: IUM]]
[[Category: Tame J]]
[[Category: complex (peptide transport/peptide)]]
[[Category: Wilkinson AJ]]
[[Category: peptide transport]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:21:51 2008''

Latest revision as of 10:28, 23 October 2024

OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KWKOLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KWK

Structural highlights

1jev is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OPPA_SALTY This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1jev, resolution 1.30Å

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