1hly: Difference between revisions
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==SOLUTION STRUCTURE OF HONGOTOXIN 1== | ==SOLUTION STRUCTURE OF HONGOTOXIN 1== | ||
<StructureSection load='1hly' size='340' side='right'caption='[[1hly | <StructureSection load='1hly' size='340' side='right'caption='[[1hly]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1hly]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLY OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[1hly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Centruroides_limbatus Centruroides limbatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HLY FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 25 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hly OCA], [https://pdbe.org/1hly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hly RCSB], [https://www.ebi.ac.uk/pdbsum/1hly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hly ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/KAX25_CENLM KAX25_CENLM] Potent selective inhibitor of Kv1.1/KCNA1, Kv1.2/KCNA2, Kv1.3/KCNA3 voltage-gated potassium channels. Weak inhibitor of Kv1.6/KCNA6 potassium channel.<ref>PMID:9446567</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/1hly_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/1hly_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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==See Also== | ==See Also== | ||
*[[Potassium channel toxin|Potassium channel toxin]] | *[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Centruroides limbatus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Blanc | [[Category: Blanc E]] | ||
[[Category: Darbon | [[Category: Darbon H]] | ||
[[Category: Gerster | [[Category: Gerster U]] | ||
[[Category: Gruber | [[Category: Gruber HJ]] | ||
[[Category: Hahn | [[Category: Hahn C]] | ||
[[Category: Kaufmann | [[Category: Kaufmann WA]] | ||
[[Category: Knaus | [[Category: Knaus HG]] | ||
[[Category: Koschak | [[Category: Koschak A]] | ||
[[Category: Obermair | [[Category: Obermair G]] | ||
[[Category: Pragl | [[Category: Pragl B]] | ||
[[Category: Prinz | [[Category: Prinz H]] | ||
[[Category: Schutz | [[Category: Schutz G]] | ||
[[Category: Trieb | [[Category: Trieb M]] | ||