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==GURMARIN, A SWEET TASTE-SUPPRESSING POLYPEPTIDE, NMR, 10 STRUCTURES==
==GURMARIN, A SWEET TASTE-SUPPRESSING POLYPEPTIDE, NMR, 10 STRUCTURES==
<StructureSection load='1gur' size='340' side='right' caption='[[1gur]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='1gur' size='340' side='right'caption='[[1gur]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1gur]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gymnema_sylvestre Gymnema sylvestre]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1gur]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gymnema_sylvestre Gymnema sylvestre]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GUR FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gur OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gur RCSB], [http://www.ebi.ac.uk/pdbsum/1gur PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gur OCA], [https://pdbe.org/1gur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gur RCSB], [https://www.ebi.ac.uk/pdbsum/1gur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gur ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GUR_GYMSY GUR_GYMSY] Suppresses strongly the sweet taste responses in the rat with high specificity to sucrose, glucose, glycine, and saccharin. This effect is reversible, but complete recovery of the suppressed responses required at least 3h. Gurmarin showed no effect or only a very weak effect on the sweet taste sensation in humans.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1gur" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Gymnema sylvestre]]
[[Category: Gymnema sylvestre]]
[[Category: Aimoto, S]]
[[Category: Large Structures]]
[[Category: Akasaka, K]]
[[Category: Aimoto S]]
[[Category: Arai, K]]
[[Category: Akasaka K]]
[[Category: Imoto, T]]
[[Category: Arai K]]
[[Category: Ishima, R]]
[[Category: Imoto T]]
[[Category: Morikawa, S]]
[[Category: Ishima R]]
[[Category: Yoshimura, S]]
[[Category: Morikawa S]]
[[Category: Suppressing protein]]
[[Category: Yoshimura S]]
[[Category: Sweet taste-suppressing protein]]
[[Category: Sweet-taste]]

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