1c5t: Difference between revisions

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 ==STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1-BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR==
-<StructureSection load='1c5t' size='340' side='right' caption='[[1c5t]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
+<StructureSection load='1c5t' size='340' side='right'caption='[[1c5t]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1c5t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C5T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C5T FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1c5t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C5T FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ESP:THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDINE'>ESP</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ESP:THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDINE'>ESP</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c5t OCA], [http://pdbe.org/1c5t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1c5t RCSB], [http://www.ebi.ac.uk/pdbsum/1c5t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1c5t ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c5t OCA], [https://pdbe.org/1c5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c5t RCSB], [https://www.ebi.ac.uk/pdbsum/1c5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c5t ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/1c5t_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/1c5t_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 29: / Line 31: @@
 ==See Also==
-*[[Trypsin|Trypsin]]
+*[[Trypsin 3D structures|Trypsin 3D structures]]
+*[[Urokinase 3D Structures|Urokinase 3D Structures]]
 == References ==
 <references/>
@@ Line 35: / Line 38: @@
 </StructureSection>
 [[Category: Bos taurus]]
-[[Category: Trypsin]]
+[[Category: Large Structures]]
-[[Category: Chan, H]]
+[[Category: Chan H]]
-[[Category: Katz, B A]]
+[[Category: Katz BA]]
-[[Category: Luong, C]]
+[[Category: Luong C]]
-[[Category: Mackman, R]]
+[[Category: Mackman R]]
-[[Category: Martelli, A]]
+[[Category: Martelli A]]
-[[Category: Radika, K]]
+[[Category: Radika K]]
-[[Category: Sprengeler, P A]]
+[[Category: Sprengeler PA]]
-[[Category: Wang, J]]
+[[Category: Wang J]]
-[[Category: Wong, L]]
+[[Category: Wong L]]
-[[Category: Hydrolase]]
-[[Category: S1 site inhibitor]]
-[[Category: Selective]]
-[[Category: Structure-based drug design]]
-[[Category: Thrombin]]
-[[Category: Urokinase]]