1c49: Difference between revisions

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OCA

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 ==STRUCTURAL AND FUNCTIONAL DIFFERENCES OF TWO TOXINS FROM THE SCORPION PANDINUS IMPERATOR==
-<StructureSection load='1c49' size='340' side='right' caption='[[1c49]], [[NMR_Ensembles_of_Models | 18 NMR models]]' scene=''>
+<StructureSection load='1c49' size='340' side='right'caption='[[1c49]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1c49]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C49 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C49 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1c49]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C49 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c49 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1c49 RCSB], [http://www.ebi.ac.uk/pdbsum/1c49 PDBsum]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 18 models</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c49 OCA], [https://pdbe.org/1c49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c49 RCSB], [https://www.ebi.ac.uk/pdbsum/1c49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c49 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/KAX72_PANIM KAX72_PANIM] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family), but with a lower affinity than PiTX-K alpha.<ref>PMID:8660410</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 13: / Line 17: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1c49" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Potassium channel toxin|Potassium channel toxin]]
+*[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Pandinus imperator]]
-[[Category: Blaustein, M P]]
+[[Category: Blaustein MP]]
-[[Category: Klenk, K C]]
+[[Category: Klenk KC]]
-[[Category: Matteson, D R]]
+[[Category: Matteson DR]]
-[[Category: Rogowski, R S]]
+[[Category: Rogowski RS]]
-[[Category: Tenenholz, T C]]
+[[Category: Tenenholz TC]]
-[[Category: Weber, D J]]
+[[Category: Weber DJ]]
-[[Category: Alpha-k toxin family]]
-[[Category: Neurotoxin]]
-[[Category: Nmr solution structure]]
-[[Category: Potassium channels blocker]]
-[[Category: Scorpion toxin]]
-[[Category: Toxin]]