1f8t: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (11 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==FAB (LNKB-2) OF MONOCLONAL ANTIBODY, CRYSTAL STRUCTURE== | |||
<StructureSection load='1f8t' size='340' side='right'caption='[[1f8t]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1f8t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F8T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f8t OCA], [https://pdbe.org/1f8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f8t RCSB], [https://www.ebi.ac.uk/pdbsum/1f8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f8t ProSAT]</span></td></tr> | |||
</table> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/1f8t_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f8t ConSurf]. | |||
<div style="clear:both"></div> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 was determined in two crystal forms by the X-ray method of molecular replacement at 2.2 and 2.9 A resolutions. The spatial structure of the protein and the stereochemistry of its antigen-binding site were analyzed. | |||
[Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms],Fokin AV, Afonin PV, Mikhailova IIu, Tsygannik IN, Mareeva TIu, Nesmeianov VA, Pangborn W, Lee N, Duax W, Siszak E, Pletnev VZ Bioorg Khim. 2000 Aug;26(8):571-8. PMID:11040993<ref>PMID:11040993</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 1f8t" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[Monoclonal | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Afonin | [[Category: Afonin PV]] | ||
[[Category: Fokin | [[Category: Fokin AV]] | ||
[[Category: Mareeva | [[Category: Mareeva TI]] | ||
[[Category: Mikhailova | [[Category: Mikhailova II]] | ||
[[Category: Tsygannik | [[Category: Tsygannik IN]] | ||
Latest revision as of 02:57, 21 November 2024
FAB (LNKB-2) OF MONOCLONAL ANTIBODY, CRYSTAL STRUCTUREFAB (LNKB-2) OF MONOCLONAL ANTIBODY, CRYSTAL STRUCTURE
Structural highlights
Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedThe three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 was determined in two crystal forms by the X-ray method of molecular replacement at 2.2 and 2.9 A resolutions. The spatial structure of the protein and the stereochemistry of its antigen-binding site were analyzed. [Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms],Fokin AV, Afonin PV, Mikhailova IIu, Tsygannik IN, Mareeva TIu, Nesmeianov VA, Pangborn W, Lee N, Duax W, Siszak E, Pletnev VZ Bioorg Khim. 2000 Aug;26(8):571-8. PMID:11040993[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
|
| ||||||||||||||||