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==CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR==
==CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR==
<StructureSection load='1dqd' size='340' side='right' caption='[[1dqd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1dqd' size='340' side='right'caption='[[1dqd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1dqd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DQD FirstGlance]. <br>
<table><tr><td colspan='2'>[[1dqd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DQD FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dqd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dqd RCSB], [http://www.ebi.ac.uk/pdbsum/1dqd PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dqd OCA], [https://pdbe.org/1dqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dqd RCSB], [https://www.ebi.ac.uk/pdbsum/1dqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dqd ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dq/1dqd_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dq/1dqd_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dqd ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1dqd" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Antibody|Antibody]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Sandbox 20009|Sandbox 20009]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Brzozowski, A M.]]
[[Category: Brzozowski AM]]
[[Category: Bywater, R P.]]
[[Category: Bywater RP]]
[[Category: Hubbard, R E.]]
[[Category: Hubbard RE]]
[[Category: Pike, A C.W.]]
[[Category: Pike ACW]]
[[Category: Roberts, S M.]]
[[Category: Roberts SM]]
[[Category: Skovgaard, R N.]]
[[Category: Skovgaard RN]]
[[Category: Svendsen, I.]]
[[Category: Svendsen I]]
[[Category: Vissing, H.]]
[[Category: Vissing H]]
[[Category: Wright, L M.]]
[[Category: Wright LM]]
[[Category: Antigen binding site]]
[[Category: Complementarity-determining region]]
[[Category: Fab]]
[[Category: Glucagon receptor]]
[[Category: Heavy chain]]
[[Category: Immune system]]
[[Category: Light chain]]
[[Category: Monoclonal antibody]]
[[Category: Receptor antagonist]]
[[Category: Typical immunoglobulin fold]]

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