2pm1: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:2pm1.jpg|left|200px]]<br /><applet load="2pm1" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2pm1, resolution 1.60&Aring;" />
-'''Derivative of human alpha-defensin 1 (HNP1)'''<br />
-==Disease==
+==Derivative of human alpha-defensin 1 (HNP1)==
-Known disease associated with this structure: Mental retardation, X-linked, South African type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300243 300243]]
+<StructureSection load='2pm1' size='340' side='right'caption='[[2pm1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2pm1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PM1 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAB:2,4-DIAMINOBUTYRIC+ACID'>DAB</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pm1 OCA], [https://pdbe.org/2pm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pm1 RCSB], [https://www.ebi.ac.uk/pdbsum/2pm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pm1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DEF1_HUMAN DEF1_HUMAN]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pm/2pm1_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pm1 ConSurf].
+<div style="clear:both"></div>
-==About this Structure==
+==See Also==
-PM1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PM1 OCA].
+*[[Defensin 3D structures|Defensin 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Lu, W.]]
+[[Category: Lu W]]
-[[Category: Lubkowski, J.]]
+[[Category: Lubkowski J]]
-[[Category: Pazgier, M.]]
+[[Category: Pazgier M]]
-[[Category: antimicrobial]]
-[[Category: defensin derivative]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:30:52 2008''