2bnq: Difference between revisions
No edit summary |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Structural and kinetic basis for heightened immunogenicity of T cell vaccines== | ==Structural and kinetic basis for heightened immunogenicity of T cell vaccines== | ||
<StructureSection load='2bnq' size='340' side='right' caption='[[2bnq]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2bnq' size='340' side='right'caption='[[2bnq]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bnq]] is a 5 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2bnq]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BNQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bnq OCA], [https://pdbe.org/2bnq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bnq RCSB], [https://www.ebi.ac.uk/pdbsum/2bnq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bnq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CTG1B_HUMAN CTG1B_HUMAN] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bn/2bnq_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bn/2bnq_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bnq ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 29: | Line 30: | ||
==See Also== | ==See Also== | ||
*[[Beta-2 microglobulin|Beta-2 microglobulin]] | *[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]] | ||
*[[ | *[[MHC 3D structures|MHC 3D structures]] | ||
*[[T-cell receptor|T-cell receptor]] | *[[MHC I 3D structures|MHC I 3D structures]] | ||
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Bossi | [[Category: Large Structures]] | ||
[[Category: Boultier | [[Category: Bossi G]] | ||
[[Category: Cerundolo | [[Category: Boultier JM]] | ||
[[Category: Chen | [[Category: Cerundolo V]] | ||
[[Category: Choi | [[Category: Chen J-L]] | ||
[[Category: Dunbar | [[Category: Choi EML]] | ||
[[Category: Esnouf | [[Category: Dunbar PR]] | ||
[[Category: Griffiths | [[Category: Esnouf RM]] | ||
[[Category: Held | [[Category: Griffiths G]] | ||
[[Category: Jackobsen | [[Category: Held G]] | ||
[[Category: Jones | [[Category: Jackobsen BK]] | ||
[[Category: Lissin | [[Category: Jones EY]] | ||
[[Category: Lissin NM]] | |||
[[Category: Renner | [[Category: Renner C]] | ||
[[Category: Rizkallah | [[Category: Rizkallah PJ]] | ||
[[Category: Sami | [[Category: Sami M]] | ||
[[Category: Sewell | [[Category: Sewell A]] | ||
[[Category: Stewart-Jones | [[Category: Stewart-Jones G]] | ||
[[Category: Wooldridge | [[Category: Wooldridge L]] | ||
[[Category: | [[Category: Van der Merwe PA]] | ||