2bdn: Difference between revisions

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<StructureSection load='2bdn' size='340' side='right'caption='[[2bdn]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
<StructureSection load='2bdn' size='340' side='right'caption='[[2bdn]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2bdn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BDN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2bdn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BDN FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bdn OCA], [http://pdbe.org/2bdn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bdn RCSB], [http://www.ebi.ac.uk/pdbsum/2bdn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bdn ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bdn OCA], [https://pdbe.org/2bdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bdn RCSB], [https://www.ebi.ac.uk/pdbsum/2bdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bdn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CCL2_HUMAN CCL2_HUMAN]] Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.  
[https://www.uniprot.org/uniprot/CCL2_HUMAN CCL2_HUMAN] Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bd/2bdn_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bd/2bdn_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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*[[Antibody 3D structures|Antibody 3D structures]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]]
*[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]]
*[[User:Coline Perrin/CCL2|User:Coline Perrin/CCL2]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Bailly, V]]
[[Category: Bailly V]]
[[Category: Boriack-Sjodin, P A]]
[[Category: Boriack-Sjodin PA]]
[[Category: Jarpe, M]]
[[Category: Jarpe M]]
[[Category: Reid, C]]
[[Category: Reid C]]
[[Category: Rushe, M]]
[[Category: Rushe M]]
[[Category: Vlijmen, H van]]
[[Category: Van Vlijmen H]]
[[Category: Antibody-antigen complex]]
[[Category: Immune system]]

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