1wiq: Difference between revisions

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==STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TRIGONAL CRYSTAL FORM==
==STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TRIGONAL CRYSTAL FORM==
<StructureSection load='1wiq' size='340' side='right' caption='[[1wiq]], [[Resolution|resolution]] 5.00&Aring;' scene=''>
<StructureSection load='1wiq' size='340' side='right'caption='[[1wiq]], [[Resolution|resolution]] 5.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wiq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WIQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wiq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WIQ FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wiq OCA], [http://pdbe.org/1wiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wiq RCSB], [http://www.ebi.ac.uk/pdbsum/1wiq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wiq ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wiq OCA], [https://pdbe.org/1wiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wiq RCSB], [https://www.ebi.ac.uk/pdbsum/1wiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wiq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.  
[https://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/1wiq_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/1wiq_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[CD4|CD4]]
*[[CD4 3D structures|CD4 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hendrickson, W A]]
[[Category: Large Structures]]
[[Category: Kwong, P D]]
[[Category: Hendrickson WA]]
[[Category: Wu, H]]
[[Category: Kwong PD]]
[[Category: Glycoprotein]]
[[Category: Wu H]]
[[Category: Immunoglobulin fold]]
[[Category: Mhc lipoprotein]]
[[Category: Polymorphism]]
[[Category: T-cell]]
[[Category: Transmembrane]]

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