1t8d: Difference between revisions
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==Structure of the C-type lectin domain of CD23== | ==Structure of the C-type lectin domain of CD23== | ||
<StructureSection load='1t8d' size='340' side='right'caption='[[1t8d | <StructureSection load='1t8d' size='340' side='right'caption='[[1t8d]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1t8d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1t8d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T8D FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t8d OCA], [https://pdbe.org/1t8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t8d RCSB], [https://www.ebi.ac.uk/pdbsum/1t8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t8d ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t8d OCA], [https://pdbe.org/1t8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t8d RCSB], [https://www.ebi.ac.uk/pdbsum/1t8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t8d ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t8/1t8d_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t8/1t8d_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Gould | [[Category: Gould HJ]] | ||
[[Category: Grundy | [[Category: Grundy GJ]] | ||
[[Category: Hibbert | [[Category: Hibbert RG]] | ||
[[Category: McDonnell | [[Category: McDonnell JM]] | ||
[[Category: Sutton | [[Category: Sutton BJ]] | ||
[[Category: Teriete | [[Category: Teriete P]] | ||