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==X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4==
==X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4==
<StructureSection load='1rnf' size='340' side='right' caption='[[1rnf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1rnf' size='340' side='right'caption='[[1rnf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1rnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RNF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1rnf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RNF FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rnf OCA], [http://pdbe.org/1rnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rnf RCSB], [http://www.ebi.ac.uk/pdbsum/1rnf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1rnf ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rnf OCA], [https://pdbe.org/1rnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rnf RCSB], [https://www.ebi.ac.uk/pdbsum/1rnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rnf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RNAS4_HUMAN RNAS4_HUMAN]] This RNase has marked specificity towards the 3' side of uridine nucleotides.  
[https://www.uniprot.org/uniprot/RNAS4_HUMAN RNAS4_HUMAN] This RNase has marked specificity towards the 3' side of uridine nucleotides.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rn/1rnf_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rn/1rnf_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
*[[Temp|Temp]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Coll, M]]
[[Category: Large Structures]]
[[Category: Gomis-Rueth, F X]]
[[Category: Coll M]]
[[Category: Llorens, R De]]
[[Category: De Llorens R]]
[[Category: Peracaula, R]]
[[Category: Gomis-Rueth FX]]
[[Category: Seno, M]]
[[Category: Peracaula R]]
[[Category: Terzyan, S S]]
[[Category: Seno M]]
[[Category: Tsushima, Y]]
[[Category: Terzyan SS]]
[[Category: Yamada, H]]
[[Category: Tsushima Y]]
[[Category: Hydrolase]]
[[Category: Yamada H]]
[[Category: Phosphodiesterase]]
[[Category: Ribonuclease]]

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