1mqa: Difference between revisions

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<StructureSection load='1mqa' size='340' side='right'caption='[[1mqa]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1mqa' size='340' side='right'caption='[[1mqa]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MQA FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MQA FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mq8|1mq8]], [[1mq9|1mq9]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LFA-1 (AlphaLbeta2) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mqa OCA], [https://pdbe.org/1mqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mqa RCSB], [https://www.ebi.ac.uk/pdbsum/1mqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mqa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mqa OCA], [https://pdbe.org/1mqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mqa RCSB], [https://www.ebi.ac.uk/pdbsum/1mqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mqa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN]] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.  
[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mq/1mqa_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mq/1mqa_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dong, Y]]
[[Category: Dong Y]]
[[Category: Jun, C D]]
[[Category: Jun C-D]]
[[Category: Liu, J H]]
[[Category: Liu J-H]]
[[Category: Shimaoka, T]]
[[Category: Shimaoka T]]
[[Category: Springer, T A]]
[[Category: Springer TA]]
[[Category: Takagi, J]]
[[Category: Takagi J]]
[[Category: Wang, J H]]
[[Category: Wang J-H]]
[[Category: Xiao, T]]
[[Category: Xiao T]]
[[Category: Yang, Y]]
[[Category: Yang Y]]
[[Category: Zhang, R]]
[[Category: Zhang R]]
[[Category: Designed disulfide bridge]]
[[Category: Immune system]]
[[Category: Rossmann fold]]

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