1evs: Difference between revisions

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 ==CRYSTAL STRUCTURE OF HUMAN ONCOSTATIN M==
-<StructureSection load='1evs' size='340' side='right' caption='[[1evs]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+<StructureSection load='1evs' size='340' side='right'caption='[[1evs]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1evs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EVS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1evs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EVS FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1evs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1evs RCSB], [http://www.ebi.ac.uk/pdbsum/1evs PDBsum]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-<table>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1evs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evs OCA], [https://pdbe.org/1evs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1evs RCSB], [https://www.ebi.ac.uk/pdbsum/1evs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1evs ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ONCM_HUMAN ONCM_HUMAN] Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).<ref>PMID:1542792</ref> <ref>PMID:1542793</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 13: / Line 17: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1evs" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
@@ Line 18: / Line 23: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Bravo, J.]]
+[[Category: Large Structures]]
-[[Category: Deller, M C.]]
+[[Category: Bravo J]]
-[[Category: Heath, J K.]]
+[[Category: Deller MC]]
-[[Category: Hudson, K R.]]
+[[Category: Heath JK]]
-[[Category: Ikemizu, S.]]
+[[Category: Hudson KR]]
-[[Category: Jones, E Y.]]
+[[Category: Ikemizu S]]
-[[Category: 4-helix bundle]]
+[[Category: Jones EY]]
-[[Category: Cytokine]]
-[[Category: Gp130 binding cytokine]]